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Frank Carveth is becoming increasingly concerned about his ex-wife Nola's secretive treatment at the sinister 'Somafree Institute of Psychoplasmics'. Headed by cult figure Dr Raglan, his controversial and extreme methods seek to unleash his patients rage which take on physical manifestations.

As Nola's increasingly psychoticanger is vented during her sessions, brutal murders befall those at whom it's directed. When Frank's daughter is abducted he is led to Raglan's Insitute and a terrifying, repellant final confrontation, renowned as one of the most notorious scenes in horror cinema.